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. 2024 Apr 27;10(9):e30462. doi: 10.1016/j.heliyon.2024.e30462

Fig. 4.

Fig. 4

O-1602 can improve METH-induced microglial activation and neuroinflammation. (A) Representative images of Iba-1 immunofluorescence. (B) Analysis of Iba-1 immunofluorescence. (C) Length analysis of Iba-1 immunofluorescent. (D) Representative bands of Western blot. (The original image is provided in the Supplementary file). (F–G) Expression levels of NLRP3, Caspase-1, and ASC proteins. Scale bars = 100 μm, 20 μm, and 5 μm. Compared with the Vehicle group, **P < 0.01, ***P < 0.001; compared with the METH group, #P < 0.05, ##P < 0.01.