Table 1.

Common CPA factors identified in the screens for the PAS of CPEB2 and CCND2 genes

			CPEB2 PAS	CCND2 PAS
#	Complexes	Genes	P adj	P adj	PAS binding*
1	CPSF	WDR33**	6.24E-162	1.22E-69	+
2		CPSF1	1.09E-102	2.50E-15	+
3		CPSF2	1.37E-12	1.76E-10	+
4		CPSF3	3.23E-07	0.0145424	+
5		CPSF4	8.38E-100	4.61E-36	+
6		FIP1L1	5.92E-08	0.0007598	+
7	CSTF	CSTF1	2.27E-19	5.93E-05	+
8		CSTF3	1.02E-08	1.04E-16	+
9	CFI	NUDT21	4.87E-08	0.0042814	+
10	CPA scaffold	SYMPK	1.52E-09	3.57E-05	+
11	CFII	PCF11	0.06263***	0.0010556	+
12	CTD kinase	CCNK	7.11E-05	0.0001607	−
13		CDK12	0.000815	0.0001589	−

*Affinity purification and mass spectrometry results from Shi et al. (17).

**The highest confidence enrichment in the two screens.

***P_adj <0.25, but >0.05.

+: Binding to RNA containing a canonical PAS with the AAUAAA hexamer. −: No PAS binding was observed.