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. 2024 May 8;7:0364. doi: 10.34133/research.0364

Fig. 9.

Fig. 9.

The tumor immune microenvironment modulation by Oxa@HMI Gel via regulating intratumoral microbiota on orthotopic colorectal tumor-bearing Balb/c mice. Representative flow cytometric images (A) and the corresponding quantitative analysis (B) of DCs (CD80+CD86+ gated by CD11c+) in TME after diverse treatments (n = 3). Representative flow cytometric images (C) and the corresponding quantitative analysis (D) of the ratio of M1 (CD86+) to M2 (CD206+) macrophages (gated by CD11b+F4/80+) in TME after various treatments (n = 3). Representative flow cytometric images (E) and the corresponding quantitative analysis (F) of MDSCs (Gr-1+ gated by CD11b+) infiltrated in TME after various treatments (n = 3). The data are presented as the mean ± SD. *P < 0.05, **P < 0.01.