Half-life time of Novichok agents' degradation by acetohydroxamate salts using different cations and various solvent mixtures.

Agent	AHA salt	% DMSOa	k obs (min−1)	t 1/2 (min)
A-230	AHA Na	0	—b	<2b
	AHA Na	20	—	<2
	AHA Na	50	—	<2
	AHA K	0	—	<2
	AHA K	20	—	<2
	AHA K	50	—	<2
	AHA DEA	0	—	<2
	AHA DEA	20	—	<2
	AHA DEA	50	—	<2
A-232	AHA Na	0	0.1924	3.6
	AHA Na	20	—	<3.5
	AHA Na	50	0.0872	7.9
	AHA K	0	—	<2
	AHA K	20	—	<3
	AHA K	50	0.0938	7.4
	AHA DEA	0	0.1474	4.7
	AHA DEA	20	0.1440	4.8
	AHA DEA	50	0.0166	41.7
A-234	AHA Na	0	0.07825	8.86
	AHA Na	20	0.03905	17.75
	AHA Na	50	0.02068	33.51
	AHA K	0	0.08161	8.49
	AHA K	20	0.04566	15.18
	AHA K	50	0.02007	34.53
	AHA DEA	0	0.06982	9.93
	AHA DEA	20	0.03003	23.08
	AHA DEA	50	0.00489	141.88

^aPercent of DMSO in a solution of DMSO/H₂O (v/v).

^bDue to NMR time scale limitations, more accurate values of t_1/2 and k_obs couldn't be determined.