Table 1.

Clinical trials of targeted tumor glycosylation vaccines in phase 2 and subsequent research stages.

	Vaccine	Target	Type	Conditions	Phase		ClinicalTrials.gov ID	Study Start	Study Status
1	Tecemotide	MUC1	Vaccine	Lung neoplasmsNon-small cell lung carcinoma	2		NCT00157209	2000.08	Completed
				Non-small cell lung carcinomaLung neoplasms	2		NCT00157196	2005.04	Completed
				Non-small cell lung cancer	3	NCT00409188		2007.01	Completed
				Multiple myeloma	2	NCT01094548		2008.01	Completed
				Non-small cell lung cancer	1/2	NCT00960115		2008.12	Completed
				Lung cancer	2	NCT00828009		2011.01	Completed
				Colon carcinomaRectum carcinoma	2	NCT01462513		2011.08	Completed
				Prostate cancer	2	NCT01496131		2011.10	Completed
				Rectal cancer	2	NCT01507103		2012.02	Completed
2	ETBX-061	MUC1	Vaccine	Triple-negative breast cancer	1/2	NCT03387085		2018.03	Active, not recruiting
				Head and neck cancerHead and neck neoplasms	1/2	NCT04247282		2020.06	Completed
3	TG4010	MUC1	Vaccine	Non-small cell lung carcinoma	2/3	NCT00415818		2005.12	Completed
				Recurrent Stage I-IV non-small cell lung cancer	2	NCT02823990		2016.12	Completed
4	CVac	MUC1	Vaccine	Epithelial ovarian cancer	2	NCT01068509		2010.07	Completed
5	ImMucin	MUC1	Vaccine	Multiple myeloma	1/2	NCT01232712		2010.09	Completed
6	BEC2	GD3	Vaccine	Non-small cell lung carcinoma	3	NCT00037713		1998.09	Completed
				Lung cancer	3	NCT00006352		1999.09	Completed
7	GD2L/GD3L-KLH/OPT-821	GD2/GD3	Bivalent vaccine	Neuroblastoma	1/2	NCT00911560		2009.05	Active, not recruiting
8	GM2/GD2L/GD3L-KLH/OPT-821	GM2/GD2/GD3	Trivalent vaccine	Sarcoma	2	NCT01141491		2010.06	Completed
9	Racotumomab	NeuGcGM3	Vaccine	Advanced non-small cell lung cancer	2	NCT01240447		2009.09	Completed
				Neuroblastoma	2	NCT02998983		2016.11	Completed
10	OBI-822	Globo-H	Vaccine	Triple-negative breast cancer	3	NCT03562637		2018.12	Recruiting
11	OPT-822/OPT-821	Globo-H	Vaccine	Metastatic breast cancer	2	NCT01516307		2011.12	Completed
				Triple-negative breast cancer	3	NCT03562637		2018.12	Recruiting
12	OBI-833/OBI-821	Globo-H	Vaccine	Esophageal cancer	2	NCT05376423		2022.06	Recruiting
				Non-small cell lung cancer	2	NCT05442060		2022.07	Recruiting
13	STn-KLH	sTn	Vaccine	Breast cancer	3	NCT00003638		1999.01	Completed
				Breast neoplasms	2	NCT00046371		2002.08	Completed

Note: 1. Data source: https://www.clinicaltrials.gov/;

2. Clinical trials whose status was shown to be terminated and unknow were not included.