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The mechanism diagram illustrates the crosstalk between Se-AA metabolism and various cell types in the TME. A) The multiple action of Se-AAs on tumor cell-related pathways. B) The functions of Se-AAs in programming macrophage immune responses. C) Se-AAs promote T-cell proliferation, differentiation, and cytotoxicity. D) Se-AAs boost the antitumor activities of NK cells.
