Table 4.
Screening performance characteristics of hypo-attenuating berry sign (HBS) in predicting the presence of ruptured aneurysm in patients with subarachnoid hemorrhage
| Value | Sensitivity | Specificity | PPV | NPV | Kappa |
|---|---|---|---|---|---|
| Overall | |||||
| Reader1 | 77.5(69.2 - 84.2) | 68.2(45.1 - 85.3) | 93.5(86.5 - 97.1) | 34.1(20.9 - 50.0) | 0.734 |
| Reader2 | 79.8(71.7 - 86.2) | 73.7(48.6 - 89.9) | 95.4(89.0 - 98.3) | 35.0(21.1 - 51.7) | |
| Aneurysm size ≤ 5mm | |||||
| Reader1 | 63.5(50.4 - 75.0) | 68.2(45.1 - 85.3) | 85.1(71.1 - 93.3) | 39.5(24.5 - 56.5) | 0.703 |
| Reader2 | 68.3(55.2 - 79.1) | 73.7(48.6 - 89.9) | 89.6(76.6 - 96.1) | 41.2(25.1 - 59.2) | |
| Aneurysm size > 5mm | |||||
| Reader1 | 90.9(80.6 - 96.3) | 68.2(45.1 - 85.3) | 89.6(79.1- 95.3) | 71.4(47.7 - 87.8) | 1.000 |
| Reader2 | 90.9(80.6 - 96.3) | 73.7(48.6- 89.9) | 92.3(82.2- 97.1) | 70.0(45.7 - 87.2) | |
| Patient with single aneurysm | |||||
| Reader1 | 84.8(75.9 - 91.0) | 71.4(47.7 - 87.8) | 93.3(85.5 - 97.3) | 50.0(31.7 - 68.3) | 0.766 |
| Reader2 | 87.9(79.4 - 93.3) | 77.8(51.9 - 92.6) | 95.6(88.5 - 98.6) | 53.8(33.7 - 72.9) | |
| Ruptured aneurysm & | |||||
| Reader1 | 86.5(78.4 - 92.0) | 83.3(57.7 - 95.6) | 97.0(90.8 - 99.2) | 50.0(31.7 - 68.3) | 0.772 |
| Reader2 | 88.3(80.5 - 93.4) | 77.8(51.9 - 92.6) | 96.1(89.7- 98.7) | 51.9(32.4 - 70.8) | |
Data are presented with 95% confidence interval. PPV: positive predictive value; NPV: negative predictive value. &: In 2 patients with 4 aneurysms the origin of bleeding could not be confirmed.