Fig. 1. (a) Chemical structures of the Ir(iii) photosensitizers Ir1–Ir6 and MMP+. (b) Electron spin resonance spectra of Ir6 and MPP+ upon incubation with the 1O2-specific scavenger 2,2,6,6-tetramethylpiperidine in the dark or upon light irradiation (L). (c) Electron spin resonance spectra of Ir6 and MPP+ upon incubation with the scavenger 5,5-dimethyl-1-pyrroline-N-oxide in the dark or upon light irradiation (L). (d). The subcellular distribution of A375 cells upon incubation with Ir6 (10 μM) for 6 h to determine the metal content inside the major organelles. L = two-photon laser irradiation at 720 nm, 40 mW, 120 s.
