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A) Schematic diagram illustrating the fabrication process of the engineered exosomes (Sep@Exo)‐encapsulating hydrogel. B) The Sep@Exo‐encapsulating hydrogel system was injected into femur defects in diabetic rats to facilitate bone regeneration. This system integrates with host bone tissues, exhibits excellent self‐healing properties, and provides sustained release of Sep@Exo to maintain ER homeostasis.
