Figure 5.

The gene cluster corresponding to the trp operon for tryptophan biosynthesis. (a) The gene cluster table computationally generated with P = 40% and (b) the manually refined table as represented in the KEGG ortholog group table. The columns in these tables represent groups of orthologous genes, which are annotated with the KEGG pathway map numbers and similarity weights in (a) and with the EC numbers in (b). The shading in (b) denotes possible operon structures, which is better viewed by the coloring at the KEGG web site (http://www.genome.ad.jp/kegg/ortholog/tab00400.html ). The gene names in parentheses are alternative names, except for HP1280 which contains a frameshift (no amino acid sequence). Eco, Escherichia coli; Hin, Haemophilus influenzae; Hpy, Helicobacter pylori; Bsu, Bacillus subtilis; Mtu, Mycobacterium tuberculosis; Ctr, Chlamydia trachomatis; Mja, Methanococcus jannashii; Mth, Methanobacterium thermoautotrophicum; Afu, Archaeoglobus fulgidus.