Table 1.

Currently Available Near-POC HCV Assays

	Cepheid Xpert HCV VL and Xpert HCV VL Fingersticka		GeneDrive HCV IDb	Molbio Truenat HCVc
Sample type	Plasma	Capillary blood	Plasma	Plasma, capillary blood
Sensitivity, %	100	98	99	95
Specificity, %	97	99	100	99
Sample preparation	Centrifugation required, all subsequent steps are integrated	Fully integrated	Centrifugation required; additional off-board sample preparation steps (several pipetting steps)	Centrifugation required for testing from plasma; a separate device required for sample preparation (both plasma and whole blood); pipetting steps
Time to result, min	110	60	Approximately 120	60
Regulatory status	CE-IVD, WHO PQ	CE-IVD	CE-IVD	India
Power supply	Needs an electricity supply	Needs an electricity supply	Needs an electricity supply	Batteries
Data analysis	PC	PC	Integrated	Integrated

Abbreviations: WHO PQ, World Health Organization prequalification, CE-IVD, CE-marked in vitro diagnostics.

^a https://www.cepheid.com/en/tests/Virology/Xpert-HCV-Viral-Load; https://www.cepheid.com/en/tests/Virology/Xpert-HCV-VL-Fingerstick.

^b https://supply.unicef.org/s0003968.html.

^c https://www.molbiodiagnostics.com/product_details.php?id=22.