Table 2.

Results of the confirmatory analysis of the endpoints

Endpoint	Placebo (n = 56)	Verum (n = 54)	p value
Discomfort sum score at day 10 Mean (SD), median, range	4.7 (7.8), 5.0, -13 to 24	7.3 (8.1), 7.0, –18 to 23	0.024
Efficacy assessment by the investigator at the end of the study n (%)
Complete healing at day 10	26 (46)	36 (67)	0.037*
Number of open abscesses (day 10)	40 (71)	36 (67)	0.036*
Complete healing	19 (48)	26 (72)
Therapy
Successful	27 (48)	38 (70)	0.021 *
Partially successful	12 (21)	7 (13)
Not successful	17 (30)	9 (17)
Mean abscess size [mean (SD)], cm
Baseline	2.2 (0.8)	2.3 (1.0)	0.9
Day 10	0.7 (0.8)	0.5 (0.9)	0.07

^*Fisher's exact test.