Table 2.
Thiotepa 10mg/kg | Thiotepa 20mg/kg | ||||
---|---|---|---|---|---|
Outcomes | Number | Probability (95%CI) |
Number | Probability (95%CI) |
P Value |
Neutrophil recovery | 90 | 124 | |||
28-day | 99(88, 100)% | 99 (88, 100)% | 0.88 | ||
Platelet recovery | 90 | 124 | |||
28-day | 81 (72, 88)% | 83 (75, 88)% | 0.77 | ||
Non-relapse mortality | 90 | 128 | 128 | ||
1-year | 6 (2, 12)% | 4 (1, 8)% | 0.66 | ||
3-year | 13 (6, 25)% | 7 (3, 14)% | 0.27 | ||
Progression/relapse | 90 | 128 | |||
1-year | 8 (3, 15)% | 7 (4, 13)% | 0.85 | ||
3-year | 15 (7, 26)% | 13 (6, 21)% | 0.67 | ||
Progression-free Survival | 90 | 128 | |||
1-year | 86 (77, 92)% | 89 (82, 93)% | 0.60 | ||
3-year | 71 (56, 82)% | 80 (70, 88)% | 0.25 | ||
Overall survival | 90 | 128 | |||
1-year | 93 (86, 97)% | 93 (86, 96)% | 0.85 | ||
3-year | 79 (64, 88)% | 83 (71, 90)% | 0.56 |