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. 2024 May 8;23(1):e0143. doi: 10.1097/CLD.0000000000000143

TABLE 1.

Identifying HBV reactivation

Original serologies Original state Change in laboratory studies indicating reactivation
HBsAg-positive Inactive chronic HBV HBV DNA undetectable → HBV DNA detectable
or
HBV DNA increase by 100-fold
HBV DNA variable Occult chronic HBV
HBsAg-negative
Anti-HBc–positive
Resolved HBV HBsAg-negative → HBsAg-positive
or
HBV DNA undetectable → HBV DNA detectable