Table 4.
Comparisons of organ involvement rate among patients with positive anti-SSA, positive anti-SSB, both positive, and both negative groups
| Anti-SSA positive group | Anti-SSB positive group | Double-positive group | Double-negative group | χ2 | P | |
|---|---|---|---|---|---|---|
| n = 301 | n = 2 | n= 168 | n = 80 | |||
| Skin mucosal involvement rate | 54 (17.90%) | 0 (0.00%) | 28 (16.70%) | 12 (15.00%) | 0.541 | 0.886 |
| Musculoskeletal involvement rate | 92 (30.60%) | 1 (50.00%) | 51 (30.40%) | 30 (37.50%) | 2.253 | 0.496 |
| Renal system involvement rate | 7 (2.30%) | 0 (0.00%) | 5 (3.00%) | 0 (0.00%) | 3.451 | 0.358 |
| Renal tubular acidosis | 7 (2.30%) | 0 (0.00%) | 5 (3.00%) | 0 (0.00%) | 3.451 | 0.358 |
| Respiratory system involvement rate | 53 (17.60%) | 0 (0.00%) | 28 (16.70%) | 8 (10.00%) | 2.904 | 0.389 |
| Interstitial pneumonia | 40 (13.30%) | 0 (0.00%) | 16 (9.50%) | 5 (6.30%) | 4.050 | 0.256 |
| Digestive system involvement rate | 73 (24.30%) | 1 (50.00%) | 28 (16.70%) | 8 (10.00%) | 5.126 | 0.154 |
| Autoimmune hepatitis | 23 (7.60%) | 1 (50.00%) | 5 (3.00%) | 11 (13.80%) | 15.076 | 0.007 |
| Blood system involvement rate | 95 (31.60%) | 0 (0.00%) | 25 (14.90%) | 12 (15.00%) | 19.353 | <0.001 |
| Immune thrombocytopenia | 36 (12.00%) | 0 (0.00%) | 16 (9.50%) | 5 (6.30%) | 2.646 | 0.449 |
| Thyroid involvement rate | 58 (19.30%) | 0 (0.00%) | 25 (14.90%) | 12 (15.00%) | 1.866 | 0.612 |