Fig. 4.

Interaction and binding pose of the four lead compounds and reference inhibitor (Ro 61–8048)in the active site; 3′-Hydroxy-alpha-naphthoflavone (Grey), 3′-Hydroxy-ss-naphthoflavone (Black), Genkwanin(Red), Apigenin (Yalow) and Ro 61–8048 (Blue).