Table 1.

Molecular docking score of 17 flavonoid phyto-ligands for KMO'sactive site.

Rank	Compound	PubChem CID	Binding Energy (kcal/mol)
1	3′-Hydroxy-alpha-naphthoflavone	13707046	−10.0
2	3′-Hydroxy-ss-naphthoflavone	688843	−9.9
3	Genkwanin	5281617	−9.2
4	Apigenin	5280443	−9.1
5	Ro 61–8048 (reference inhibitor) 3′,5′-Dihydroxyflavone	5282337 45933941	−9.1 −9.0
6	Isopratol	676307	−8.9
7	7,3′-Dihydroxyflavone	5391140	−8.8
8	4′-Methoxy-6-methylflavone	688682	−8.8
9	2,6,7-Trihydroxy-9-methylxanthen-3-one	72721	−8.6
10	3-O-Methylquercetin	5280681	−8.6
11	5,7,3′-Trimethoxyflavone	12150586	−8.5
12	7,4′-Dimethoxyflavone	5322058	−8.4
13	7,3′-dimethoxyflavone	688672	−8.4
14	6-Hydroxy-4′-methoxyflavone	688679	−8.4
15	5,7-Dimethoxyflavone	88881	−8.4
16	5,6,7-Trimethoxyflavone	442583	−8.4
17	4′,5-Dimethoxyflavone	688669	−8.2