TABLE 3.
Clinical and laboratory characteristics of deaths associated with Viridans Group Streptococci bacteraemia.
Patient number | Age category† | Gender | Nutrition‡ | HIV status | Diagnosis | Underlying condition | CRP | WBC | SIRS score | pSOFA | Antibiotic susceptibility | Empiric antibiotic used | Time interval in days (culture to outcome) | Time to positivity of culture (hours) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Neonate | F | Underweight | Neg | Pneumonia | Premature | 1 | 8.73 | 2 | 8 | Sensitive | Ampicillin/gentamycin | 7 | 10 |
2 | Neonate | M | Underweight | Neg | NOS | Premature | 19 | 3.13 | NC | NC | Resistant ampicillin | Unknown | 16 | 12 |
3 | Neonate | F | Normal | Neg | NOS | DiGeorge/CHD | 23 | 33.8 | NC | NC | Not done | Unknown | 19 | 10 |
4 | Neonate | F | Normal | Neg | NOS | Spina bifida | 8 | 11.8 | NC | NC | Not done | Unknown | 10 | 6 |
5 | Infant | M | Underweight | Neg | Pneumonia | Trisomy21/CHD | 1 | 9.95 | 2 | 5 | Resistant cefotaxime | Meropenem | 1 | 8 |
6 | Infant | F | Underweight | Pos | NOS | BPD | 102 | 8.96 | 0 | 5 | Sensitive | Meropenem/vancomycin | 44 | CSF (no time stated) |
7 | Infant | F | Underweight | Neg | Pneumonia | Premature | 18 | 7.32 | NC | NC | Sensitive | Unknown | 1 | 12 |
8 | Child | F | Normal | Neg | Pneumonia | Cerebral palsy | 300 | 15.4 | NC | NC | Sensitive | Unknown | 1 | 19 |
CRP, C-reactive protein; WBC, white blood cell; SIRS, systemic inflammatory response syndrome; pSOFA, paediatric sequential organ failure assessment; Neg, negative; Pos, positive; NOS, nosocomial sepsis; CHD, congenital heart disease; BPD, bronchopulmonary dysplasia; NC, not calculable (missing data); F, female; M, male.
, Neonate, infant child;
, Normal underweight stunted wasted.