Receiver operating characteristic curves for the detection of reticular pseudodrusen by the convolutional neural network DenseNet from (A) fundus autofluorescence (FAF) images and (B) their corresponding color fundus photography (CFP) images. The performance of the 4 ophthalmologists on the same test sets is shown by 4 single points. In (B), the performance of the reading center grading of the CFP images also is shown as a single point. In all cases, the ground truth is the reading center grading of the FAF images. AUC = area under the receiver operating characteristic curve. Ophthalmologist 1 was a second-year retinal fellow, ophthalmologist 2 was a first-year retinal fellow, ophthalmologist 3 had been a retinal specialist for 35 years, and ophthalmologist 4 had been a retinal specialist for 2 years.