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Effects of Sim treatment on the lung coefficients and inflammation in silica-induced rats. (A) H&E staining (200×, n = 6). (B) The lung coefficients. (C) Alveolar inflammation scores quantified by H&E staining. The levels of IL-1β (D), IL-6 (E) and TNF-α (F) in lung tissues. Data are presented as the means ± SD, n = 6. *p < 0.05, **p < 0.01 vs. the control group; #p < 0.05, ##p < 0.01 vs. the silica group
