Fig. 6.

Effects of Sim treatment on the AMPK-NOX pathway in silica-induced rats. (A) The western blotting bands of p-AMPK, AMPK and GAPDH in lung tissues among different groups (n = 3). The gels/blots are corpped, and full-length gels/blots are presented in Fig. S2. (B) The relative protein expression of p-AMPK/AMPK. (C) The western blotting bands of NOX4, NOX2, p-p47phox, p47phox, p40phox, p22phox and GAPDH in lung tissues among different groups (n = 3). The gels/blots are corpped, and full-length gels/blots are presented in Fig. S3. The relative protein expressions of NOX4 (D), NOX2 (E), p-p47phox/p47phox (F), p40phox (G), and p22phox (H). Data are presented as the means ± SD, n = 3. *p < 0.05, **p < 0.01 vs. the control group; ^#p < 0.05, ^##p < 0.01 vs. the silica group