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. 2023 Sep 21;2(9):e111. doi: 10.1002/jex2.111

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© 2023 The Authors. Journal of Extracellular Biology published by Wiley Periodicals, LLC on behalf of the International Society for Extracellular Vesicles.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Cellular CRISPR/Cas9 delivery systems and their potential cargo divided into physical, viral and non‐viral subgroups. TRIAMF (transmembrane internalization assisted by membrane filtration), iTOP (induced transduction by osmocytosis and propane betaine (PB)), AV (Adenovirus), AAV (adeno‐associated virus), LV/RV (lentivirus/retrovirus), CPP (cell penetrating peptide), LNP (lipid nanoparticle), PNP (polymeric nanoparticle), MNP (metallic nanoparticle), EV (extracellular vesicle). Created with BioRender.com.