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. 2024 May 9;20(5):e1011253. doi: 10.1371/journal.pgen.1011253

Fig 5. SYD-2 is required for UNC-104 dependent of SVp carriers.

Fig 5

(A) Schematic of the PLM neuron. The red box highlights the region of imaging. (B) SNG-1::GFP in the cell body, process and synapses of PLM neurons of syd-2(ok217) and unc-104(e1265tb120), and their doubles with lrk-1(km17) and apb-3(ok429). Scale bar: 10 μm. (C) CTNS-1::mCherry in the cell body, process and synapses of PLM neurons of syd-2(ok217) and unc-104(e1265tb120), and their doubles with apb-3(ok429). Scale bar: 10 μm. (D) Quantitation of fraction of total moving SNG-1-carrying vesicles co-transporting CTNS-1 in WT, unc-104(e1265tb120), syd-2(ok217), and unc-104; syd-2 from kymograph analysis of sequential dual color imaging at 1.3 fps. P-value > 0.05 (Mann–Whitney Test, all comparisons to WT); ns: not significant; Number of animals (N) > 20 for unc-104; syd-2; Number of vesicles (n) >1000.