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. 2024 Apr 29;20(4):e1012068. doi: 10.1371/journal.pcbi.1012068

Fig 8. In vitro assays of a novel driver gene LRP1 predicted by PDRWH.

Fig 8

(A) The expression of LRP1 was detected between GES-1 and GC cells. (B) The expression of LRP1 was detected between GC tissues and adjacent tissues using Immunohistochemical analysis. (C) Overall Survival analysis of LRP1 based on GEPIA. (D) HGC-27 cells transfected with siRNA by real-time PCR and Western Blot. (E) Wound healing assay following knockdown of LRP1 in HGC-27 cells. (F) Apoptosis detection for HGC-27 cells transfected with siRNA. (G) Proliferation detection for HGC-27 cells transfected with siRNA using EdU assay. (H) Cell cycle profile of control and LRP1 knockdown cells. GAPDH protein is used as control. All cell assays were performed in triplicate. The error bars indicate SD of three independent experiments. *P < 0.05, **P < 0.01 using the two-sided Student’s t test.