Table 3.
Comparison of PFAS binding to human TTR in this study and two literature sources.
Chemical Name | CASRN | EC50 (μM) this study | EC50 (μM) Ren et al., 2016. | EC50 (μM) Weiss et al., 2009. |
---|---|---|---|---|
Perfluoroheptanoic acid | 375-85-9 | 0.40 | 1.128 | 1.565 |
Perfluorononanoic acid | 375-95-1 | 0.41 | 1.977 | 2.737 |
Potassium perfluorooctanesulfonate | 2795-39-3 | 0.43 | 0.13 | 0.94 |
Perfluorooctanoic acid | 335-67-1 | 0.44 | 0.378 | 0.949 |
Potassium perfluorohexanesulfonate | 3871-99-6 | 0.49 | 0.594 | 0.717 |
Potassium perfluorobutanesulfonate | 29,420-49-3 | 0.71 | 13.33 | nta |
Perfluorodecanoic acid | 335-76-2 | 0.71 | 1.623 | 8.954 |
Perfluorooctanesulfonamide | 754-91-5 | 0.73 | nt | 6.124 |
Not tested = nt.