Table 3.
Laboratory parameters compared between the survival and death group.
| Variables | All (n = 394) | Survival (n = 302) | Death (n = 92) | P |
|---|---|---|---|---|
| Laboratory parameters | ||||
| Viral load (TCID 50/mL)* | < 0.001 | |||
| < 103 | 232 (58.9) | 208 (68.9) | 24 (26.1) | |
| 103–106 | 134 (34.0) | 90 (29.8) | 44 (47.8) | |
| > 106 | 28 (7.1) | 4 (1.3) | 24 (26.1) | |
| Leukocytes (109/L) | 2.61 (1.69, 4.70) | 2.67 (1.62, 4.66) | 2.50 (1.75, 5.00) | 0.847 |
| Neutrophils (109/L) | 1.63 (1.03, 3.38) | 1.60 (1.03, 3.73) | 1.67 (1.04, 2.68) | 0.944 |
| Lymphocyte (109/L) | 0.61 (0.39, 0.96) | 0.62 (0.40, 0.96) | 0.55 (0.34, 0.97) | 0.142 |
| Erythrocyte (1012/L) | 4.44 ± 0.57 | 4.43 ± 0.53 | 4.46 ± 0.71 | 0.737 |
| Hemoglobin (g/L) | 134.39 ± 18.27 | 134.36 ± 17.08 | 134.47 ± 21.81 | 0.967 |
| Platelets (109/L) | 51 (34, 66) | 53 (36, 68) | 40 (30, 57) | < 0.001 |
| ALT (U/L) | 66 (40, 124) | 62 (38, 110) | 95 (51, 164) | < 0.001 |
| AST (U/L) | 149.0 (73.3, 296.6) | 125.4 (65.0, 245.6) | 294.2 (137.0, 488.4) | < 0.001 |
| CK (U/L) | 543 (230, 1292) | 428 (209, 912) | 1017 (450, 2259) | < 0.001 |
| CK-MB (U/L) | 33.9 (19.9, 57.1) | 28.2 (18.4, 46.4) | 61.2 (31.2, 109.8) | < 0.001 |
| LDH (U/L) | 631 (347, 955) | 552 (322, 847) | 904 (567, 1737) | < 0.001 |
| α-HBDH (U/L) | 426 (253, 692) | 380 (240, 605) | 645 (364, 1071) | < 0.001 |
| K (mmol/L) | 3.81 (3.42, 4.14) | 3.77 (3.40, 4.06) | 4.03 (3.68, 4.39) | < 0.001 |
| Na (mmol/L) | 134.4 (131.0, 138.0) | 134.0 (131.0, 138.0) | 135.2 (131.0, 138.6) | 0.429 |
| Cl (mmol/L) | 99 (96, 103) | 99 (96, 103) | 100 (96, 104) | 0.536 |
| BUN (mmol/L) | 5.0 (3.8, 7.3) | 4.6 (3.4, 6.7) | 6.1 (4.7, 10.6) | < 0.001 |
| sCr (mmol/L) | 70.0 (58.0, 88.4) | 66.7 (55.0, 80.4) | 87.5 (67.3, 114.9) | < 0.001 |
| PT (s) | 13.0 (12.2, 14.9) | 12.8 (12.1, 14.5) | 14.2 (12.7, 15.8) | < 0.001 |
| APTT (s) | 43.4 (37.6, 51.3) | 41.5 (37.0, 48.1) | 51.9 (44.3, 66.3) | < 0.001 |
| Fibrinogen (g/L) | 2.01 (1.72, 2.31) | 2.07 (1.78, 2.34) | 1.81 (1.48, 2.19) | < 0.001 |
| TT (s) | 19.4 (18.3, 20.7) | 19.1 (18.1, 20.2) | 20.6 (19.4, 23.2) | < 0.001 |
| D-dimer (μg/L) | 3.52 (1.74, 8.13) | 2.90 (1.34, 5.73) | 8.78 (3.67, 17.04) | < 0.001 |
*The differences were statistically significant between surviving patients and deceased patients in the viral load < 103 group compared with the 103–106 group (p < 0.001), in the < 103 group compared with the > 106 group (p < 0.001), and in the 103–106 group compared with the > 106 group (p < 0.001).
ALT alanine aminotransferase, AST aspartate aminotransferase, CK creatinine kinase, CK-MB creatinine kinase myocardial b fraction, LDH lactate dehydrogenase, α-HBDH α-Hydroxybutyrate dehydrogenase, K potassium, Na sodium, Cl chloride, BUN Blood urea nitrogen, sCr serum creatinine, PT prothrombin time, APTT activated partial thromboplastin time, TT thrombin time.
Significant values are in bold.