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. 2024 Mar 8;52(6):1653–1664. doi: 10.1007/s10439-024-03478-0

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Bayesian K_D and binding site concentration assay analysis of ACE2 and spike protein. Indicated are the binding curve for the interaction (left panel), the probability density plot indicating the convergence of the K_D and spike binding site concentration based on the analysis (middle panel) and the modal distribution of the K_D derived from the fit of the data (right panel).