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. 2024 May 9;9:123. doi: 10.1038/s41392-024-01849-6

Fig. 1.

Fig. 1

Neutralization of distinct SARS-CoV-2 sub-lineages by XBB reinfection and WSK-V102C vaccination sera. a The mutation frequency heatmap of BA.2.87.1 and other related lineages. Only mutations with a frequency higher than 0.75 are shown. Deletions are shown in cyan. Mutation frequency data was retrieved from the outbreak.info website. b Neutralization of different SARS-CoV-2 variant PsVs by sera collected from two groups of individuals who had previously experienced BA.5/BF.7 breakthrough infections following three doses of inactivated vaccines: one group were reinfection with XBB virus, the other group were boosted with the WSK-V102C vaccine. c In parallel comparison of neutralization GMTs against distinct Omicron subvariants by sera collected from individuals with XBB reinfection or with WSK-V102C booster vaccinations. d Neutralization of PsVs representing BA.2.87.1’s single and combined NTD deletions by sera collected from individuals with XBB reinfection or with WSK-V102C booster vaccination. Values above the symbols denote GMTs and their fold increase or decrease relative to WT (for panel b) or BA.2 (for panel d). Dotted lines indicate the threshold of detection (40 for all the cohorts). P values were determined by using multiple Mann–Whitney tests. WT wild-type