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NK2 antagonizes paracrine, but not autocrine, HGF/SF-induced subcutaneous melanoma growth. One million 37-32 melanoma cells were injected under the back skin of 2- to 3-month-old wild-type (WT), HGF/SF transgenic, NK2 transgenic, and HGF/SF-NK2 bitransgenic mice; tumor sizes were measured; and growth rates were calculated.
