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. 2024 Apr 26;15:1359611. doi: 10.3389/fmicb.2024.1359611

Table 2.

Clinical assessment at d21 (healthy calves) or disease manifestation (diarrheic calves).

Breed (B) Pooled SEM Colostrum source (CS) Pooled SEM Health status (HS) Pooled SEM P-values*
Variables Holstein (n = 29) Jersey (n = 22) Dam (n = 28) Mixed (n = 23) Healthy (n = 24) Diarrhea (n = 27) B CS HS B × CS B × HS CS × HS
Mean age at clinical assessment (d) 23 23 0.71 23 23 0.75 22 24 0.63 NS NS 0.004 NS NS NS
Mean rectal body temperature (°C) 39.2 39.0 0.07 39.2 39.0 0.07 38.9 39.3 0.06 NS NS 0.0004 NS NS NS
Health scores (median score) Range Range Range
Nasal 0 0 0–1 0 0 0–1 0 0 0–1 NS NS NS NS NS NS
Ocular 0 0 0–1 0 0 0–1 0 0 0–1 NS NS NS NS NS NS
Ear 0 0 0–2 0 0 0–2 0 0 0–2 NS NS 0.001 NS NS NS
Cough 0 0 0–1 0 0 0–1 0 0 0–1 NS NS NS NS NS NS
Feces 2 1 0–3 2 1 0–3 0 3 0–3 NS NS <0.0001 NS NS NS
Navel 0 0 0–2 0 0 0–2 0 0 0–2 NS NS NS NS NS NS
Joints 1 0 0–2 0 0 0–2 0 1 0–2 <0.0001 NS NS NS NS NS
Coat 0 0 0–2 0 0 0–2 0 0 0–2 NS NS NS NS NS NS
Dehydration 0 0 0–2 0 0 0–2 0 0 0–1 NS NS 0.03 NS NS NS
Mucus membranes 0 0 0–1 0 0 0–1 0 0 0–1 NS NS 0.05 NS NS NS

*NS, not statistically significant. Clinical assessment criteria are available on OSF.