Table 3.
Genera and adjusted p-values (q) associated with health status during the pre-weaning period.
| Taxonomical classification | q-values* | ||||
|---|---|---|---|---|---|
| ASV | Phylum | Genus | Pre-disease transition† | During diarrhea† | Transition to recovery† |
| ASV1 | Actinomycetota (Actinobacteriota) | Bifidobacterium | 0.0003 | 0.0002 | NS |
| ASV3 | Pseudomonadota (Proteobacteria) | Escherichia-Shigella | 0.04 | 0.04 | 0.02 |
| ASV5 | Bacteroidota | Alloprevotella | 0.002 | 0.0002 | 0.0001 |
| ASV6 | Actinomycetota (Actinobacteriota) | Collinsella | NS | 0.03 | NS |
| ASV8 | Bacillota (Firmicutes) | Peptostreptococcus | 0.006 | 0.02 | 0.006 |
| ASV9 | Bacteroidota | Prevotella | NS | 0.04 | 0.02 |
| ASV12 | Fusobacteriiota | Fusobacterium | 0.04 | NS | NS |
| ASV16 | Bacteroidota | Prevotella_9 | 0.002 | 0.007 | 0.002 |
| ASV18 | Bacillota (Firmicutes) | Ligilactobacillus | 0.0002 | 0.0009 | 0.0002 |
| ASV20 | Bacillota (Firmicutes) | Rikenellaceae RC9 gut group | 0.04 | NS | 0.03 |
| ASV22 | Bacillota (Firmicutes) | Phascolarctobacterium | NS | 0.02 | 0.03 |
| ASV24 | Actinomycetota (Actinobacteriota) | Olsenella | NS | NS | 0.03 |
| ASV25 | Bacteroidota | NA | 0.02 | 0.03 | NS |
| ASV28 | Bacteroidota | Prevotella_7 | 0.01 | 0.0009 | 0.0002 |
| ASV41 | Bacteroidota | Prevotellaceae UCG-001 | NS | NS | 0.03 |
| ASV44 | Bacillota (Firmicutes) | Lachnospiraceae UCG-004 | 0.02 | 0.03 | NS |
| ASV48 | Bacillota (Firmicutes) | Faecalicoccus | 0.02 | 0.001 | 0.0004 |
| ASV50 | Bacteroidota | Prevotellaceae UCG-003 | NS | NS | 0.04 |
| ASV58 | Bacillota (Firmicutes) | NA | 0.0004 | 0.001 | 0.0002 |
| ASV66 | Bacillota (Firmicutes) | NA | 0.03 | NS | NS |
| ASV67 | Bacillota (Firmicutes) | Erysipelatoclostridium | NS | 0.004 | 0.001 |
| ASV75 | Thermodesulfobacteriota (Desulfobacterota) | Desulfovibrio | 0.02 | 0.03 | 0.02 |
| ASV78 | Verrucomicrobioota | Akkermansia | NS | 0.04 | 0.03 |
| ASV82 | Bacillota (Firmicutes) | Flavonifractor | 0.003 | 0.0003 | 0.0001 |
| ASV88 | Bacillota (Firmicutes) | NA | 0.03 | NS | 0.03 |
| ASV91 | Bacillota (Firmicutes) | NA | 0.002 | 0.007 | 0.0009 |
| ASV92 | Bacillota (Firmicutes) | Allisonella | 0.006 | 0.02 | 0.007 |
| ASV93 | Bacillota (Firmicutes) | Dialister | 0.006 | 0.02 | 0.006 |
| ASV96 | Bacillota (Firmicutes) | Anaerofilum | 0.04 | NS | 0.05 |
| ASV104 | Bacteroidota | Barnesiella | NS | NS | 0.03 |
| ASV109 | Bacillota (Firmicutes) | Lachnospiraceae FCS020 group | 0.02 | 0.03 | NS |
| ASV112 | Bacillota (Firmicutes) | Intestinibacter | 0.002 | 0.007 | 0.0008 |
| ASV132 | Bacteroidota | Butyricimonas | 0.01 | 0.02 | 0.01 |
* q = adjusted p-values determined using Benjamini–Hochberg procedure; NS, not statistically significant. †Pre-disease transition, transition from pre-disease (d7) to disease manifestation; during diarrhea, at d21 (healthy calves) or disease manifestation (diarrheic calves); Transition to recovery, from disease manifestation to weaning (d83).