Table 1.

Prevalence of ever smoking in men and women in the Dutch population and in SSc patients followed in the Leiden CCISS cohort in 2015 and 2021

Age range (years)	Dutch population (ever-smokers), n (%)	SSc patients (ever-smokers), n (%)	P-value
2015
Men
25–44	2 126 000 (55)	11 (82)	0.078
45–64	2 385 000 (65)	25 (56)	0.345
≥65	1 362 000 (79)	12 (67)	0.291
Women
25–44	2 116 000 (48)	49 (43)	0.492
45–64	2 369 000 (61)	106 (55)	0.198
≥65	1 644 000 (52)	74 (50)	0.705
2021
Men
25–44	2 193 000 (52)	9 (56)	0.820
45–64	2 409 000 (60)	53 (70)	0.127
≥65	1 604 000 (77)	16 (56)	0.054
Women
25–44	2 154 000 (43)	41 (34)	0.240
45–64	2 413 000 (54)	152 (45)	0.043
≥65	1 849 000 (55)	91 (55)	0.985