FIG. 4.

Deduced amino acid sequence of the novel DNA-binding protein hCGBP. Underlined amino acid residues 27 to 73, 164 to 208, and 485 to 591 identify three cysteine-rich domains. The lysine- and arginine-rich basic region (aa 321 to 360) is indicated by a dashed underline. Heavily underlined residues (aa 430 to 471) denote a predicted coiled-coil domain. Horizontal arrows denote the region encoded by the 720-bp hCGBP cDNA clone recovered from ligand screening. The vertical arrow denotes the 3′ end of the truncated hCGBP cDNA clone that retains DNA-binding activity. This sequence has been deposited in the GenBank database (accession no. AF149758). (B) Diagram of hCGBP showing the relative positions of the identified protein domains.