Figure 1.

The transcripts encoded by the DMD gene and Dp71 dystrophin transcript splice variants. (A) Chromosomal localisation of the DMD gene and its encoded transcripts. The vertical dashes indicate individual exons. The location of the first exons is indicated by the red boxes. Specific splice variants are indicated on the left. (B) Schematic representation of Dp71 splice variants. Dp7b and Dp71ab lack exon 78 and have an alternative exon 79, resulting in an alternative C-terminus. N, N terminal domain; C, C terminal domain; DMD, Duchenne muscular dystrophy.