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. 2024 Apr 25;26:e51949. doi: 10.2196/51949

Table 2.

Baseline sociodemographic and medical sample characteristics (n=218).

Variable Interventiona (n=99) Controlb (n=119)
Age (years), mean (SD; range) 55 (11; 20-77) 58 (10; 35-76)
Sex, n (%)

Female 65 (65.7) 67 (56.3)

Male 34 (34.3) 52 (43.7)
Cancer type, n (%)

Breast 38 (38.4) 36 (30.3)

Hematological 27 (27.3) 34 (28.6)

Lung 9 (9.1) 12 (10.1)

Urogenital 6 (6.1) 14 (11.8)

Gastrointestinal 7 (7.1) 11 (9.2)

Head-neck 3 (3) 4 (3.4)

Gynecologic 3 (3.0) 3 (2.5)

Other 6 (6.1) 5 (4.2)
Relapse, n (%) 7 (7.1) 12 (10.1)
Time (months) since cancer diagnosis, mean (SD) 25 (18) 24 (16)
Psychotherapeutic support during study participation, n (%) 15 (15.2) 17 (14.3)
Digital therapeutic use before study, n (%) 15 (15.2) 14 (11.8)
NCCN Distress Thermometer≥5c, n (%) 71 (71.8) 86 (72.3)
Anxiety (HADS-A)≥8d, n (%) 56 (56.7) 67 (56.3)
Depression (HADS-D)≥8e, n (%) 42 (42.4) 41 (34.5)
Exclusion in per-protocol analysisf, n (%) 49 (49.5) 45 (40.9)

Psychotherapeutic support during study 15 (15.2) 17 (14.3)

Prior use of investigated digital therapeutic 15 (15.2) 28 (23.5)

Missing questionnaire 5 (5.1) 5 (4.2)

Digital therapeutic was not used up until the 5- to 9-week period 17 (17.2) N/A

aIntervention=12-week access to digital therapeutic app intervention+usual care.

bControl=usual care.

cNCCN Distress Thermometer: National Comprehensive Cancer Network Distress Thermometer (at baseline, clinically significant level of distress≥5).

dHADS-A: Hospital Anxiety and Depression Scale, anxiety subscale (German version, at baseline, cutoff score ≥8).

eHADS-D: Hospital Anxiety and Depression Scale, depression subscale (German version, at baseline, cutoff score ≥8).

fMultiple reasons are possible within 1 patient, and cases do not add up to the total number.