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Structural model of CCR3. (A) Structures of CCR3 generated in silico, highlighting Open and Close state. Structures are represented as surfaces seen from above. (B) The structure of SB 328437. (C) Binding site of CCR3 with SB 328437 located. (D) Common residues involved in ligand binding, these correspond mainly to hydrophobic residues, with certain residues, such as cysteine 106 and 183, involved in ligand recognition.
