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. 2024 Apr 23;13(9):734. doi: 10.3390/cells13090734

Figure 2.

Figure 2

VPA treatment does not affect mRNA expression of REST/NRSF target genes in the injured brain. Gene expression analyses by qPCR 7 days post-injury (dpi) relative to Ppia. (A) Rest/Nrsf; (B) Bdnf; (C) Ntrk2; (D) Grin2a; (E) Gria1; (F) Slc12a5; (G) Chrm4; (H) Egr1; (I) Arc; (J) Cspg4; (K) Pdgfra; (L) Syn1; (M) Snap25; (N) L1cam; (O) Bax; (P) Bcl2. CCI effects were observed, but VPA treatment had no effect on gene expression in sham or CCI groups. Data are expressed as mean ± SEM with individual values shown and p values were calculated by one-way ANOVA with post hoc Holm–Šidák correction (# p < 0.05; ## p < 0.01; ### p < 0.001; #### p < 0.0001).