Table 3.
Summary of the sequencing results of BMMF1 and BMMF2 consensus PCR in the validation collection.
| BMMFs and Tissue# |
Sequence Results | Identity | GenBank | |
|---|---|---|---|---|
| BMMF1 RCC |
1 | Sphinx1.76-related DNA, replication-competent episomal DNA MSBI2.176 | 96% | LK931492.1 |
| 2 | Sphinx1.76-related DNA, replication-competent episomal DNA HCBI3.108 | 97% | LK931495.1 | |
| 3 | BMMF1 DNA sequence, isolate C1MI.9M.1 | 94% | LR215496.1 | |
| 4 | Sphinx1.76-related DNA, replication-competent episomal DNA HCBI3.108 | 100% | LK931495.1 | |
| 5 | BMMF1 DNA sequence, isolate C1MI.15M.2 | 95% | LR215495.1 | |
| 6 | Sphinx1.76-related DNA, replication-competent episomal DNA HCBI6.159 | 95% | LK931494.1 | |
| BMMF2 RCC |
1 | BMMF2 DNA sequence, isolate C2MI.15B.17 | 83% | LR215569.1 |
| 2 | TSE-associated circular DNA isolate Sphinx 2.36 | 98% | HQ444405.1 | |
| 3 | BMMF2 DNA sequence isolate C2MI.9B.5 | 97% | LR215542.1 | |
| 4 | BMMF2 DNA sequence, isolate C2MI.15B.1 | 92% | LR215553.1 | |
| 5 | BMMF2 DNA sequence, isolate C2MI.8A.3 | 75% | LR215533.1 | |
| BMMF1 peritumoral |
1 | Sphinx1.76-related DNA, replication-competent episomal DNA HCBI3.108 |
98% | LK931495.1 |
| BMMF2 peritumoral |
1 | BMMF2 DNA sequence, isolate C2MI.9As.2 | 82% | LR215600.1 |
| 2 | TSE-associated circular DNA isolate Sphinx 2.36, complete sequence | 98% | HQ444405.1 | |
| 3 | TSE-associated circular DNA isolate Sphinx 2.36, complete sequence | 99% | HQ444405.1 | |
| 4 | TSE-associated circular DNA isolate Sphinx 2.36, complete sequence | 99% | HQ444405.1 | |
| 5 | TSE-associated circular DNA isolate Sphinx 2.36, complete sequence | 98% | HQ444405.1 | |
| 6 | TSE-associated circular DNA isolate Sphinx 2.36, complete sequence | 98% | HQ444405.1 | |
| 7 | TSE-associated circular DNA isolate Sphinx 2.36, complete sequence | 96% | HQ444405.1 | |
| 8 | TSE-associated circular DNA isolate Sphinx 2.36, complete sequence | 97% | HQ444405.1 | |
| 9 | TSE-associated circular DNA isolate Sphinx 2.36, complete sequence | 95% | HQ444405.1 |
Abbreviation: TSE, transmissible spongiform encephalopathy.