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. 2024 Apr 23;13(9):732. doi: 10.3390/cells13090732

Table 1.

Effects of LC and/or GB treatment on body weight, serum glucose homeostasis, and liver enzymes.

Groups Body Weight Glucose (mg/L) Insulin (uIU/mL) HOMA-IR ALT(U/L) AST (U/L)
Control 157.67 ± 5.28 86.17 ± 8.1 16.67 ± 1.15 3.73 ± 0.39 48.17 ± 4.67 94.5 ± 9.42
HCD 259.83 ± 5.27 acde 138.22 ± 4.22 acde 21.6 ± 3.51 e 5.1 ± 0.55 a 91.67 ± 4.18 acde 166 ± 11.08 acde
HCD + LC 218.83 ± 3.43 abe 119.12 ± 4.02 abe 18.83 ± 2.52 4.88 ± 0.46 a 62.5 ± 5.86 ab 118 ± 8.74 ab
HCD + GB 228 ± 7.48 abe 119.28 ± 4.83 abe 16.63 ± 1.31 4.78 ± 0.48 a 62 ± 5.18 ab 118.33 ± 5.47 abc
HCD + LC + GB 191.83 ± 5.19 abcd 94.76 ± 3.79 bcd 15.23 ± 1.68 b 4.087 ± 0.44 55 ± 4 b 113.33 ± 3.72 ab

All values are expressed as the mean ± SD; HOMA-IR: homeostatic model assessment for insulin resistance; ALT: alanine aminotransferase; AST: aspartate aminotransferase. The superscript letters a, b, c, d, and e indicate significant differences (p-value < 0.05) between groups in comparison with the control, HCD, HCD + LC, HCD + GB, and HCD + LC + GB groups, respectively.