ANOVA	Analysis of variance
BBD	Box-Behnken design
BCS	Biopharmaceutics Classification System
CBD	Cannabidiol
CYP	Cytochrome P
DCF-DA	Dichlorodihydrofluorescein diacetate or 2′,7′-dichlorofluorescein diacetate
DL	Drug loading
DMEM	Dulbecco’s Modified Eagle Medium
DMSO	Dimethyl sulfoxide
EE	Encapsulation efficiency
ELISA	Enzyme-linked Immunosorbent Assay
EMA	European Medicines Agency
FBS	Fetal bovine serum
FDA	Food and Drug Administration
FTIR	Fourier Transform Infrared Spectroscopy
GMS	Glyceryl monostearate
GRAS	Generally recognized as safe
HRMS	High-Resolution Mass Spectrometry
HSA	Human serum albumin
IL	Interleukin
JAKs	Janus kinases
LPS	Lipopolysaccharides
MMPs	Matrix metalloproteinases
MSC	Model selection criterion
NMR	Nuclear Magnetic Resonance
NO	Nitric oxide
OA	Osteoarthritis
PBS	Phosphate buffer solution
PDI	Polydispersity index
PPARs	Peroxisome proliferator-activated receptors
QbD	Quality-by-Design
RASFs	Rheumatoid arthritis synovial fibroblasts
RNS	Reactive nitrogen species
ROS	Reactive oxygen species
RSM	Response Surface Methodology
RT	Room temperature
SLN	Solid lipid nanoparticle
TNF-α	Tumor necrosis factor-alpha
XRD	X-ray diffraction