FIG. 2.

Functional activities of XARP constructs. (A) Inhibition of dorsal axial development by XARP. Both dorsovegetal blastomeres of four- to eight-cell embryos were injected with 2 ng of XARP mRNA and allowed to develop until control siblings reached stage 36. An uninjected embryo is shown at the bottom. (B) Axis duplication caused by a truncated form of XARP lacking the RGS domain. Two nanograms of Myc-XARPΔRGS mRNA was injected into a ventrovegetal blastomere of four- to eight-cell embryos.