Table 1.
Anthropometric, clinical, and biochemical characteristics of control and HT-treated stroke patients at 0, 45, and 90 days.
| HT Treatment (n = 4) | Contro1 (n = 4) | p-Value | ||||||
|---|---|---|---|---|---|---|---|---|
| 0 d | 45 d | 90 d | 0 d | 45 d | 90 d | Time Effect | Group Effect | |
| Sex | Men | Men | ||||||
| Age (years) | 63.8 ± 9.3 | 74.8 ± 4.8 | ||||||
| BMI (kg/m2) | 37.4 ± 8.6 | 31.5 ± 3.1 | ||||||
| Glucose (mg/dL) | 98.8 ± 7.5 | 115.5 ± 13.2 | 101.0 ± 4.1 | 119.3 ± 2.4 | 115.5 ± 16.4 | 116.3 ± 17.9 | ||
| TAG (mg/dL) | 112.5 ± 60.0 | 92.8 ± 40.7 | 101.5 ± 37.5 | 137.0 ± 55.7 | 121.8 ± 45.3 | 138.5 ± 83.3 | ||
| HDL-C (mg/dL) | 44.0 ± 13.5 | 42.5 ± 9.3 | 39.3 ± 4.2 | 41.3 ± 15.2 | 38.8 ± 2.9 | 34.3 ± 8.8 | ||
| LDL-C (mg/dL) | 98.3 ± 45.5 | 70.8 ± 19.5 | 56.5 ± 15.6 | 100.0 ± 29.0 | 58.0 ± 10.4 | 47.8 ± 21.8 | 0.008 | |
| TC (mg/dL) | 165.0 ± 48.0 | 131.8 ± 23.1 | 116.0 ± 10.6 | 169.0 ± 39.6 | 121.3 ± 13.9 | 109.5 ± 21.8 | 0.07 | |
| HbA1c (%) | 0.06 ± 0.01 | 0.06 ± 0.01 | 0.06 ± 0.01 | 0.06 ± 0.01 | 0.06 ± 0.01 | 0.06 ± 0.01 | ||
| IL-6 (pg/mL) | 9.9 ± 10.7 | 4.8 ± 4.1 | 3.3 ± 15 | 73.6 ± 130.7 | 13.3 ± 18.4 | 12.2 ± 14.2 | ||
| NO (μM) | 4.7 ± 1.9 | 5.6 ± 0.5 | 14.7 ± 9.7 | 6.1 ± 0.3 | 11.5 ± 2.4 | 8.0 ± 2.8 | 0.010 | |
| TBARS (μM) | 7.8 ± 1.2 | 10.4 ± 3.1 | 8.8 ± 2.6 | 7.0 ± 2.5 | 8.8 ± 2.4 | 11.4 ± 3.3 | 0.063 | |
| SBP (mmHg) | 144.8 ± 34.8 | 128.8 ± 8.7 | 118.8 ± 10.3 | 163.3 ± 12.0 | 121.0 ± 8.4 | 120.5 ± 7.4 | 0.004 | |
| DBP (mmHg) | 81.5 ± 9.7 | 72.3 ± 3.2 | 60.3 ± 21.1 | 92.5 ± 10.9 | 67.5 ± 5.0 | 66.8 ± 10.4 | 0.001 | |
| NIHSS | 5.3 ± 1.5 | 0.5 ± 1.0 | 0.25 ± 0.5 | 8 ± 2.5 | 2.5 ± 2.7 | 2.0 ± 2.5 | 0.001 | |
| mRs | 13 ± 1.0 | 0.0 ± 0.0 | 0.3 ± 0.5 | 3.3 ± 15 | 1.5 ± 1.3 | 1.3 ± 1.0 | <0.001 | |
| TUG (s) | – | 12.8 ± 2.9 | 13.6 ± 6.9 | – | 14.3 ± 5.5 | 11.5 ± 2.7 | ||
| FAC | – | 3.75 ± 1.0 | 3.5 ± 2.4 | – | 4 ± 1.4 | 4 ± 1.4 | ||
| HGS non-paretic limb (kg) | – | 34.1 ± 4.3 | 34.3 ± 7.2 | – | 27.2 ± 3.0 | 29.4 ± 9.76 | ||
| HGS paretic limb (kg) | – | 22.9 ± 8.0 | 24.65 ± 9.7 | – | 14.6± 11.0 | 16.4 ± 13.2 | ||
| MoCA score | – | 24.8 ± 5.0 | 24.5 ± 8.0 | – | 20 ± 8.7 | 24.3 ± 6.0 | ||
Values are expressed as mean ± SD. Only statistically (p < 0.05) or marginally (0.1 > p > 0.05) significant differences are shown. BMI: body mass index, DBP: diastolic blood pressure, FAC: Functional Ambulation Categories, HbA₁c: glycated hemoglobin, HDL-C: high-density lipoprotein cholesterol, HGS: hand-grip strength, IL-6: interleukin 6, LDL-C: low-density lipoprotein cholesterol, MoCA score: Montreal Cognitive Assessment score, mRs: modification of Rankin Scale, NIHSS: National Institutes of Health Stroke Scale, NO: nitric oxide, SBP: systolic blood pressure, TAG: triacylglycerides, TBARS: thiobarbituric acid-reactive substances, TC: total cholesterol, TUG: Timed Up and Go.