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. 2024 Apr 27;25(9):4799. doi: 10.3390/ijms25094799

Table 2.

Proteins differentially expressed in the serum of control and HT-treated stroke patients.

HT Treatment
45 vs. 0
Uniprot ID Protein Name Abbreviation Gene Fold Change p Value
000533 Neural cell adhesion molecule L1-like protein NC HL1 CHL1 1.912 0.026
Q9UGM5 Fetuin-B FETUB FETUB 1.359 0.045
P07339 Cathepsin D CATD CTSD −1.169 0.012
P04114 Apolipoprotein B-100 APOB APOB −1.655 0.014
Q9UHG3 Prenylcysteine oxidase PCYOX PCYOX1 −1.716 0.030
P02649 Apolipoprotein E APOE APOE −1.891 0.000
O95445 Apolipoprotein M APOM APOM −1.968 0.039
Q13740 CD166 antigen CD166 ALCAM −2.192 0.039
Q005469 Hormone- sensitive lipase LIPS LIPE −3.229 0.041
90 vs. 45
Uniprot ID PrSSotein name Abbreviation Gene Fold change p value
P02766v109B Transthyretinv109B TTR TTR 6.972 0.048
Q8N1N4 Keratin type I cytoskeletal 78 K2C78 KRT78 5.137 0.043
90 vs. 0
Uniprot ID Protein name Abbreviation Gene Fold change p value
P55065 Apolipoprotein A-IV APC )A4 APOA4 2.987 0.008
P06727 Glutaminyl-peptide cydotransferase QPCT QPCT 2.189 0.023
Q16769 Keratin type I cytoskeletal 14 K1C14 KRT14 1.704 0.031
P00558 Fetuin-B FETUB FETUB 1.554 0.038
P02533 Hyaluronan-binding protein 2 HABP2 HABP2 1.44 0.037
Q14520 Phosphoglycerate kinase PGK1 PGK1 −1.268 0.030
Q9UGM5 Apolipoprotein M APC DM APC DM −1.927 0.043
P02654 Apolipoprotein C-I APOC 1 APOC 1 −2.624 0.042
O95445 Apolipoprotein C-IV APOC 4 APOC4 −6.702 0.006
CONTROL
45 vs. 0
Uniprot ID Protein name Abbreviation Gene Fold change p value
P06727 Apolipoprotein A-IV APOA4 APOA4 2.903 0.032
O43505 Beta-1 4-glucuronyltransferase 1 B4GA1 B4GAT1 2.274 0.002
Q12860 Contactin-1 CNTN1 CNTN1 2.107 0.037
P01008 Antithrombin-III ANT3 SERPINC1 1.495 0.040
P06681 Complement C2 CO2 C2 1.138 0.034
P04180 Phosphatidylcholine -sterol acyltransferase LCAT LCAT −1.389 0.023
P22352 Glutathione peroxidase 3 GPX3 GPX3 −1.572 0.042
P04066 Tissue alpha-L-fucosidase FUCO FUC A1 −3.751 0.007
90 vs. 45
Uniprot ID Protein name Abbreviation Gene Fold change p value
Q6YHK3 CD109 antigen CD109 CD109 3.72 0.034
O14818 Proteasome subunit alpha type-7 PSA7 PSMA7 1.494 0.028
P35542 Serum amyloid A-4 protein SAA4 SAA4 −1.404 0.030
Q5TZA2 Rootletin CROCC CROCC −1.454 0.042
O43505 Beta-1 4-glucuronyltransferase 1 B4GA1 B4GAT1 −2.695 0.029
P00740 Coagulation factor IX FA9 F9 −3.156 0.024
P16157 Ankyrin-1 ANK1 ANK1 −9.475 0.022
90 vs. 0
Uniprot ID Protein name Abbreviation Gene Fold change p value
Q6YHK3 CD109 antigen CD109 CD109 8.496 0.016
A0A075B6H7 Probable non-functional immunoglobulin kappa variable 3-7 KV37 IGKV3 7.943 0.044
Q12860 Contactin-1 CNTN1 CNTN1 6.574 0.020
P06727 Apolipoprotein A-IV APOA4 APC )A4 3.089 0.013
P00352 Retinal dehydrogenase 1 AL1A1 ALDH1A1 1.911 0.042
P01008 Antithrombin-III ANT3 SERPINC1 1.46 0.014
P35542 Serum amyloid A-4 SAA4 SAA4 −1.805 0.025
P02652 Apolipoprotein A-II APOA2 APOA2 −1.991 0.050
P01591 Immunoglobulin J chain IGJ JCHAIN −2.23 0.025
P02654 Apolipoprotein C-I APOC1 APOC1 −3.188 0.037
P00740 Coagulation factor IX FA9 F9 −3.298 0.035
A0A0C4DH67 Immunoglobulin kappa variable 1-8 KV108 IGKV1 −3.952 0.018
O95445 Apolipoprotein M APOM APOM −3.984 0.030
P04066 Tissue alpha-L-fucosidase FUCO FUCA1 −8.264 0.035
Q03591 Complement factor H-related protein 1 FHR1 CFHR1 −26.803 0.050