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Therapeutic potential of TLRs.
| Approach | Examples | Diseases | Reference |
|---|---|---|---|
| TLR Agonists | Poly-ICLC, MEDI9197, QbG10, Resiquimod, Imiquimod | Cancer, infectious diseases, allergies, HPV | [10,11,12] |
| TLR Antagonists | TAC5, MHV370 | Autoimmune diseases (psoriasis, SLE), inflammatory conditions | [13,14] |
| Vaccine Adjuvants | Monophosphoryl Lipid A (MPL), CpG-1018, Resiquimod, Imiquimod | Infectious diseases (HBV, HCV, HIV, SARS-CoV-2, influenza, HPV) | [10,11,12] |
