Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Apr 25;15:1371220. doi: 10.3389/fendo.2024.1371220

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2024 Gu, Cooper, Lewis, Zoorob and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Expression of H3K9m1, H3K9m2, H3K9m2, CuZn-SOD, and Mn-SOD in placental trophoblasts from normal and preeclamptic pregnancies. (A) Expression of H3K9me1, H3K9me2, H3K9me3 in trophoblasts (TCs) from 7 normal (Nor) and 7 preeclamptic (PE) placentas. The bar graphs show relative expression for H3K9me1, H3K9me2, and H3K9me3 after normalized by β-actin expression in each sample. (B) Expression of CuZn-SOD and Mn-SOD in trophoblasts from 7 normal and 7 preeclamptic placentas. The bar graphs show relative expression for CuZn-SOD and Mn-SOD after normalized by β-actin expression in each sample. These data revealed that downregulation of antioxidant CuZn-SOD and Mn-SOD expression are associated with upregulation of methylated H3K9 expression in trophoblasts from preeclamptic vs. normal placentas. **p<0.01: PE-TCs vs. Nor-TCs.