Figure 4.

ABC transporters gene expression of Lucena cells transwell cultured with mesenchymal stem cells from healthy donors (MSC-H) compared with Lucena cells transwell cultured with mesenchymal stem cells from acute myeloid leukemia patients (MSC-AML). Results were obtained from a pool of cDNA samples from 3 independent experiments. Data are expressed as mean ± SEM. Dotted lines are the cutline to overexpression (RQ Log = 0.30) or inhibition (RQ Log = −0.30) of ABC transporter gene expressions. RQ: relative quantification. Dotted lines represent the significance limits of RQ (relative quantification) changed by at least two-fold: more than 2 (RQ log = 0.30) or less then 0,5 (RQ log = −0.30).