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. 2024 Apr 27;25(9):4764. doi: 10.3390/ijms25094764

Figure 2.

Figure 2

Effect of the leaf extract from C. sativa on NF-κB (A)- and AP-1 (B)-driven transcription, measured via luciferase assay and reporter plasmids. The HaCaT cells (not stimulated control, white bar) were treated with C. acnes O.D. = 0.1 (black bar) and the leaf extract (dots bar) for 24 h (A) or 48 h (B). Apigenin (20 μM) was used as a reference inhibitor of NF-κB activity (−78%). Data (n = 3) are expressed as the mean (%) ± SEM relative to C. acnes, which was arbitrarily assigned the value of 100%. ** p < 0.01 and *** p < 0.001 vs. C. acnes.