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. 2024 May 6;25(9):5050. doi: 10.3390/ijms25095050

Table 7.

Partial correlation analyses of the serum levels of adiponectin with the selected serum levels of the HDL subclasses in the HVs.

Adiponectin (µg/mL)
Model 1 Model 2 Model 3 Model 4
Variable (mg/dL) r p r p r p r p
HDL-C 0.42 0.0007 0.42 0.0009 0.40 0.0015 0.34 0.0064
HDL1-C 0.44 0.0004 0.43 0.0005 0.42 0.0007 0.41 0.0009
HDL2-C 0.45 0.0003 0.45 0.0003 0.44 0.0004 0.39 0.0015
HDL-FC 0.40 0.0012 0.40 0.0015 0.38 0.0023 0.33 0.0080
HDL1-FC 0.38 0.0025 0.37 0.0030 0.35 0.0049 0.34 0.0076
HDL2-FC 0.33 0.0088 0.34 0.0077 0.31 0.0134 0.27 0.0334
HDL1-TG 0.19 0.1425 0.19 0.1515 0.17 0.1811 0.21 0.1045
HDL-PL 0.43 0.0006 0.43 0.0006 0.40 0.0012 0.36 0.0042
HDL1-PL 0.45 0.0002 0.45 0.0003 0.43 0.0005 0.43 0.0005
HDL2-PL 0.44 0.0004 0.44 0.0003 0.43 0.0006 0.40 0.0014
HDL3-PL 0.28 0.0283 0.28 0.0267 0.27 0.0366 0.21 0.1004
HDL-apoA-I 0.32 0.0110 0.32 0.0129 0.29 0.0225 0.24 0.0648
HDL1-apoA-I 0.41 0.0009 0.41 0.0011 0.39 0.0017 0.39 0.0016
HDL2-apoA-I 0.37 0.0027 0.37 0.0031 0.35 0.0057 0.32 0.0124
HDL1-apoA-II 0.28 0.0281 0.28 0.0319 0.25 0.0462 0.29 0.0231

Spearman’s partial correlation analyses were used to evaluate the associations of the serum levels of adiponectin with the serum levels of HDL, while accounting for covariates. p-values < 0.0005 are considered statistically significant after Bonferroni correction for multiple testing and are depicted in bold. Model 1: Adjusted for age, sex, and BMI. Model 2: Adjusted for age, sex, BMI, and CRP. Model 3: Adjusted for age, sex, and waist circumference. Model 4: Adjusted for age, sex, and MetSSS. ApoA-I, apolipoprotein A-I, apoA-II, apolipoprotein A-II; BMI, body mass index; C, cholesterol; CRP, C-reactive protein; FC, free cholesterol; HDL, high-density lipoprotein; HV, healthy volunteer; MetSSS, metabolic syndrome severity score; PL, phospholipid; r, Spearman’s correlation coefficient; TG, triglyceride.