Figure 2.

Comparison of the levels of serum anti-JMJD6 antibodies (s-JMJD6-Abs) in healthy donors (HDs) and patients with acute myocardial infarction (AMI) and diabetes mellitus (DM). (a) This figure shows the levels of s-JMJD6-Abs examined by amplified luminescence proximity homogeneous assay-linked immunosorbent assay (AlphaLISA). Antibody levels are represented by Alpha photon counts and shown in a scatter dot plot; the horizontal lines represent medians, as well as the 25th and 75th percentiles. The p-values were calculated using the Kruskal–Wallis test. (b,c) The abilities of s-JMJD6-Ab levels to detect AMI (b) and DM (c) were assessed by receiver operating characteristic (ROC) curve analysis. The numbers in (b,c) are cutoff values, sensitivity (left), specificity (right), p-values, area under the curve (AUC) values, and 95% confidence intervals (95% CI).