Table 2.
Spearman’s correlation analysis between the serum anti-JMJD6 antibody levels and clinical features in the Sawara Hospital cohort.
| Parameter | Rho Value | 95% Confidence Interval | p-Value | Number of Pairs |
|---|---|---|---|---|
| Age | 0.3173 | 0.2532 to 0.3786 | <0.0001 | 839 |
| BMI * | −0.0797 | −0.1488 to −0.0098 | 0.0215 | 832 |
| IMT (r) | 0.2507 | 0.1744 to 0.3240 | <0.0001 | 640 |
| IMT (l) | 0.2661 | 0.1904 to 0.3386 | <0.0001 | 641 |
| max IMT | 0.2761 | 0.2009 to 0.3481 | <0.0001 | 642 |
| A/G | −0.1357 | −0.2047 to −0.0653 | 0.0001 | 808 |
| AST | 0.0421 | −0.0278 to 0.1116 | 0.2238 | 836 |
| ALT | −0.0180 | −0.0877 to 0.0520 | 0.6045 | 835 |
| ALP | 0.0989 | 0.0266 to 0.1701 | 0.0059 | 775 |
| LDH | 0.0541 | −0.0169 to 0.1245 | 0.1243 | 810 |
| tBil | −0.0469 | −0.1171 to 0.0237 | 0.1801 | 818 |
| CHE | −0.1352 | −0.2129 to −0.0558 | 0.0006 | 636 |
| γ-GTP | 0.0389 | −0.0334 to 0.1107 | 0.2778 | 782 |
| TP | −0.1581 | −0.2264 to −0.0883 | <0.0001 | 812 |
| ALB | −0.2019 | −0.2686 to −0.1334 | <0.0001 | 821 |
| BUN | 0.0442 | −0.0258 to 0.1137 | 0.2022 | 834 |
| Creatinin | 0.0213 | −0.0488 to 0.0912 | 0.5399 | 830 |
| eGFR | −0.0540 | −0.1274 to 0.0200 | 0.1406 | 746 |
| UA | −0.0093 | −0.0909 to 0.0723 | 0.8176 | 612 |
| AMY | −0.0430 | −0.1313 to 0.0459 | 0.3288 | 517 |
| T-CHO | −0.1239 | −0.1966 to −0.0498 | 0.0008 | 733 |
| HDL-c | −0.0222 | −0.1087 to 0.0648 | 0.6072 | 541 |
| TG | −0.0989 | −0.1813 to −0.0152 | 0.0173 | 579 |
| Na+ | 0.0093 | −0.0611 to 0.0797 | 0.7892 | 821 |
| K+ | −0.0573 | −0.1272 to 0.01320 | 0.1009 | 821 |
| Cl− | 0.0418 | −0.0287 to 0.1119 | 0.2312 | 821 |
| CRP | 0.1370 | 0.0555 to 0.2167 | 0.0007 | 604 |
| WBC | 0.0702 | 0.0003 to 0.1394 | 0.0426 | 834 |
| Neutrophils | 0.0818 | 0.004362 to 0.1583 | 0.0331 | 679 |
| Eosinophils | −0.0360 | −0.1132 to 0.04157 | 0.3486 | 679 |
| Basophils | −0.0566 | −0.1335 to 0.02095 | 0.1406 | 679 |
| Monocytes | 0.0516 | −0.02601 to 0.1285 | 0.1796 | 679 |
| Lymphocytes | −0.1083 | −0.1842 to −0.03106 | 0.0047 | 679 |
| RBC | −0.1118 | −0.1802 to −0.0422 | 0.0012 | 834 |
| HGB | −0.0830 | −0.1520 to −0.0132 | 0.0165 | 834 |
| HCT | −0.0793 | −0.1484 to −0.0095 | 0.0220 | 834 |
| MCV | 0.0879 | 0.0181 to 0.1568 | 0.0111 | 834 |
| MCH | 0.0781 | 0.0083 to 0.1472 | 0.0241 | 834 |
| MCHC | −0.0308 | −0.1004 to 0.0392 | 0.3750 | 834 |
| RDW | 0.0836 | 0.0138 to 0.1526 | 0.0158 | 834 |
| PLT | −0.0966 | −0.1653 to −0.0269 | 0.0052 | 834 |
| MPV | −0.0109 | −0.0807 to 0.0591 | 0.7540 | 834 |
| PCT | −0.0956 | −0.1644 to −0.0259 | 0.0057 | 834 |
| PDW | −0.0470 | −0.1165 to 0.0230 | 0.1751 | 834 |
| BS | 0.1343 | 0.0622 to 0.2049 | 0.0002 | 772 |
| HbA1c | 0.0571 | −0.0225 to 0.1360 | 0.1474 | 645 |
| BP | 0.0946 | 0.0102 to 0.1776 | 0.0238 | 571 |
| Smoking period | 0.1515 | 0.0761 to 0.2253 | <0.0001 | 699 |
| Alcohol frequency | 0.0449 | −0.0319 to 0.1212 | 0.2382 | 692 |
The Sawara hospital cohort includes 285 healthy donors, 65 patients with chronic cerebral infarction, 464 patients with acute cerebral infarction, 92 patients with transient ischemic attack, 19 patients with asymptomatic cerebral infarction, and 162 patients with deep and subcortical white matter hyperintensity. * BMI: body mass index. IMT (r): right-sided intima–media thickness. IMT (l): left-sided intima–media thickness. max IMT: maximum intima–media thickness. A/G: albumin/globulin ratio. AST: aspartate aminotransferase. ALT: alanine aminotransferase. ALP: alkaline phosphatase. LDH: lactate dehydrogenase. tBil: total bilirubin. CHE: choline esterase. γ-GTP: gamma-glutamyl transpeptidase. TP: total protein. ALB: albumin. BUN: blood urea nitrogen. eGFR: estimated glomerular filtration rate. UA: uric acid. AMY: amylase. T-CHO: total cholesterol. HDL-c: high-density lipoprotein cholesterol. TG: triglyceride. CRP: C-reactive protein. WBC: white blood cell count. RBC: red blood cell count. HCT: hematocrit. MCV: mean corpuscular volume. MCH: mean corpuscular hemoglobin. MCHC: mean corpuscular hemoglobin concentration. RDW: red cell distribution width. PLT: platelet count. MPV: mean platelet volume. PCT: procalcitonin. PDW: platelet distribution width. BS: blood glucose. HbA1c: glycated hemoglobin. BP: blood pressure. p-values of <0.05 are marked in bold.